Understanding a metastatic diagnosis
If your doctor suspects your cancer has metastasized, there are a number of tests he or she might do. These may include:
- Imaging tests like , , or
If your lung cancer has metastasized, it can be a shock. You may feel overwhelmed, scared, or even angry. Everyone reacts differently, but it’s important to take the time you need to absorb this information. Reach out to loved ones, family, friends, and even others with your condition for support throughout this time.
What is biomarker testing?
Biomarker testing may help your doctor better understand what is causing your lung cancer to grow. Your doctor may also refer to biomarkers as "mutations." Mutations that can contribute to cancer have been identified in NSCLC. Identified mutations include alterations in EGFR, ALK, and other proteins.
Understanding EGFR biomarkers in metastatic NSCLC
What is EGFR?
One type of biomarker is epidermal growth factor receptor, also known as EGFR. EGFR is a protein found on the surface of cells in the body. Sometimes mutations cause changes in this protein, and it becomes unusually active, which can lead to the growth and spread of cancer cells.
What is EGFR mutation-positive metastatic NSCLC?
Some metastatic NSCLC tumors will have certain types of abnormal, or mutated, EGFR genes.
About 10% to 20% of Caucasian people and 40% to 60% of Asian people diagnosed with NSCLC test positive for an EGFR mutation.